First Case of Mesenteric Extraosseous Osteosarcoma in Australia
Authors: Salim X, Paton D, Lambers A, Carey Smith R
Site: Sir Charles Gairdner Hospital, WA
Dr Lambers and colleagues at Sir Charles Gairdner Hospital Perth document the first reported case of mesenteric extraosseous osteosarcoma (EOS) in Australia. EOS, which is a bone cancer appearing outside of a bone is a rare, aggressive tumour originating in soft tissues without attachment to bone or periosteum. While EOS typically occurs in the limbs, its occurrence in the mesentery is extremely rare, with only six cases documented worldwide. Due to its rarity, the disease’s progression and optimal treatment strategies remain poorly understood and it is vital that cases and outcomes are reported to better understand the unusual disease.
EOS accounts for less than 1% of all sarcomas and behaves differently from its osseous counterpart. Mesenteric EOS is particularly rare, and existing literature offers limited guidance on diagnosis and management. Multimodal treatment combining surgery, chemotherapy, and radiotherapy may help, but outcomes remain poor. This case underscores the need for further research to understand the disease and improve therapeutic approaches.
